MyBioSource.com's E-Cadherin Polyclonal Antibody is a Goat Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot. The E-Cadherin Polyclonal Antibody was generated using CDH1, FZr, and FZR1 as the antigen and it reacts with Human, Mouse, Rat, Bovine, Canine, Chicken/Bird, Donkey, Feline, Goat, Guinea Pig, Hamster, Horse, Non-Human Primate, Porcine, Rabbit, and Sheep.
Description
E-Cadherin
Goat polyclonal to CDH1. CDH1 is a classical member of the cadherin superfamily. This protein is a calcium dependent cell-cell adhesion glycoprotein comprised consists of 5 cadherin repeats in the extracellular domain, one transmembrane domain, and a and a highly conserved intracellular domain that binds b-catenin and p120-catenin. CDH1 is involved in mechanisms regulating proliferation, mobility and cell-cell adhesions of epithelial cells. Loss of E-cadherin function or expression has been implicated in cancer metastasis and progression